Pharmacovigilance – News and Features

The cytokine IL-17 acts on two distinct brain regions – the amygdala and the somatosensory cortex – to exert two divergent effects. In the amygdala, IL-17 can elicit feelings of anxiety, while in the cortex, it promotes sociable behavior.

Contamination is one of the main roadblocks to successful cell culture. This article explores the different types of contamination, how to identify microbial contaminants in cell culture and best practices for removal and prevention.

New findings on how the gut microbiome influences drug metabolism and effectiveness could open the door to personalized medicines and better treatment outcomes.

Oxalic acid, a common molecule found in foods such as spinach and berries, may increase a patient's risk of experiencing sickness after using gadolinium-based MRI contrast agents, a new study suggests.

New research from The University of Texas at Austin could aid in improving whooping cough vaccines to once again push this disease toward eradication by targeting two key weaknesses in the infection.

MIT researchers have developed a way to rapidly manufacture specialized nanoparticles that can be used for targeted delivery of cancer drugs and other therapeutics.

A novel cell therapy approach using natural killer cells pre-complexed with a bispecific antibody, was safe and generated strong response rates for patients with refractory CD30-positive lymphoma, according to a new study.

Nitrous oxide, better known as laughing gas, can potentially transform treatment for tough-to-beat depression. This centuries-old anesthetic gas targeted specific brain cells in mice and quickly reduced symptoms, according to new research.

Solriamfetol, a new treatment for ADHD, showed a 45% reduction in symptoms in a Phase 3 trial. This treatment targets dopamine and norepinephrine reuptake and offers a safer alternative for those who don’t respond well to traditional stimulants.

University of Birmingham scientists have shown that a sequence of just three amino acids may reduce the severity of psoriasis, when applied topically in an emollient cream.