RNA-Seq – Multimedia

Despite the valuable transcriptomic information provided by probe-based spatial assays, detecting immune cell infiltration can pose challenges

According to the World Health Organization (WHO), cancer is a leading cause of death worldwide. Furthermore, recent estimates predict that as many as one in two people could develop a form of cancer in their lifetime.

Formaldehyde fixed & paraffin-embedded (FFPE) tissue blocks are one of the most commonly used and archived sample types. However, some preservation approaches can result in the degradation of RNA and hinder transcriptome profiling .

Download this listicle to discover recent examples of how single-cell analysis methods are driving forward research into cancer, aging, and drug discovery and development.

Download this listicle to explore how proteomics is being applied in drug discovery and biomedical research, food industry, agriculture, environmental science and forensics.

In this eBook, we highlight developments in cancer research through a selection of articles, interviews and graphics.

Target enrichment allows researchers to selectively capture, sequence and study specific genes or genomic regions. Carefully designed target enrichment probes that hybridize with high specificity and coverage are essential to ensuring workflow efficiency and data quality.

Researchers require spatial information and high-plex gene expression data to understand how cells interact with tumors. However, molecular subtyping within a tumor type requires additional stratification at the tissue level to facilitate meaningful subsequent gene expression analysis.

Single-cell RNA sequencing produces a substantial amount of complex data that can be a burden if you don’t have time to become an expert in bioinformatics.

Speaking at ‘Advances in Proteomics & Metabolomics’ 2022, Charlotte Stadler from SciLifeLab presented her talk on the generation of highly multiplexed immunofluorescence data and bridging the gap between research and conventional clinical pathology.