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RNA-Seq – News and Features

Cells.
News

How Immunoglobulins Influence the Aging Process

Researchers mapped aging across multiple organs, finding immunoglobulin G accumulation drives aging by increasing structural disorder and inflammation. The study offers IgG as a biomarker and uses antisense oligonucleotides to reduce aging effects.
A 3D model of a human kidney.
News

Copper Accumulation in the Body Drives Kidney Cancer Growth

Researchers at the University of Cincinnati found that copper accumulation fuels renal cell carcinoma by enhancing energy production in tumors. Elevated copper levels activate protective mechanisms that support cancer cell survival.
Blood samples in test tubes.
News

Biomarker Predicts Success of Inflammatory Bowel Disease Treatment

A new study from Charité University reveals that the biomarker Ki67 can predict if inflammatory bowel disease patients will respond to vedolizumab. Machine learning identified Ki67 levels as a marker for treatment resistance.
RNA molecule.
News

Noncoding RNAs Are Definitely Not “Junk”

Using CRISPR-Cas13, NYU researchers reveal that noncoding RNAs, previously deemed “junk,” are crucial for cell function and development. Their findings, published in Cell, identify nearly 800 essential noncoding RNAs.
A cancer cell highlighted in orange, with a target centered on it.
News

Potential New Treatment Suggested for Aggressive Prostate Cancer

Researchers have identified how mutations to CDK12 drive prostate cancer development and reported a promising treatment that targets the gene.
A molecule of DNA, showing the alpha helix structure
Article

A Guide to DNA and RNA Quantification and Quality

Discover methods for accurate DNA and RNA quantification and learn how to analyze purity and concentration to enhance reliability in molecular biology.
A plastic model of a human brain, bisected to show internal structures, with a brain cell next to it.
News

Microglia Exacerbate Damage in APOE4 Model of Alzheimer’s

New research shows that microglia, which usually clear debris, cause harmful inflammation in the presence of APOE4 protein.
A three-dimensional (3D), computer-generated image, of a group of Gram-positive, Streptococcus pneumoniae bacteria.
News

Study on Emerging Streptococcus Subspecies Sheds Light on Increased Rates of Human Infections

Researchers at Houston Methodist studied the emerging strain Streptococcus dysgalactiae subspecies equisimilis (SDSE) and its virulence. The team revealed significant insights into SDSE's genomic and transcriptomic features.
A researcher in a white lab coat and gloves sits in front of a laminar flow hood, holding a flask of cell culture.
News

First Blueprint of the Human Spliceosome Published

Researchers have created the first blueprint of the human spliceosome, the most complex and intricate molecular machine inside every cell.
T cells.
News

Sleeping Sickness Parasite Hides in Tissues To Evade Antibiotics

A study by Johns Hopkins researchers reveals that the parasite T. brucei, responsible for African sleeping sickness, uses host tissues to evade immune responses. The findings show that T. brucei generates diverse surface proteins in tissues.
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