RNA-Seq – News and Features

New research has developed a brain organoid model to study lissencephaly, a rare genetic disorder.

Two new studies from Mount Sinai’s Living Brain Project reveal that living human brain tissue shows major molecular differences compared to postmortem samples, the current research standard.

EPFL researchers uncover how transcription factor dosage reshapes cell identity, showing that even small differences in dose can steer cells toward completely different fates.

EMBL researchers and collaborators have developed SDR-seq, a breakthrough single-cell technology that captures DNA and RNA together in the same cell. Unlike earlier methods, it reveals genetic variants in non-coding regions.

A study led by EPFL shows that Urolithin A, a natural compound, can abolish high anxiety in rats by repairing mitochondrial function in their brain cells, specifically in the nucleus accumbens.

The study has generated the first wheat pan-transcriptome – a comprehensive map of gene activity across multiple wheat varieties.

New research has uncovered a mechanism that explains why brown adipose tissue is more metabolically active in females.

Researchers from Queen Mary University of London have found that the next-generation target of rapamycin (TOR) pathway inhibitor – rapalink-1 – can significantly prolong lifespan in simple fission yeast.

Researchers have shown for the first time that glioblastoma—the deadliest form of brain cancer—affects not just the brain but also erodes the skull, alters the makeup of skull marrow, and interferes with the body’s immune response.

Researchers at McGill University have developed a machine learning tool that identifies disease-related patterns in RNA expression at a finer resolution than conventional methods.