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The Immune System – News and Features

A person in a blue shirt itches their forearm.
News

Protein Behind Psoriasis Flare-Ups Identified for the First Time

The protein behind flare-ups of psoriasis and its link to the immune system have been uncovered.
Cell therapy.
News

Study Finds No Evidence CAR T-Cell Therapy Causes Secondary Cancers

A study of 783 patients treated with CAR T cell therapy found no evidence that the therapy itself caused secondary cancers. Researchers confirmed that rare cases of cancer were linked to prior treatments like chemotherapy, not CAR T therapy.
Double helix structure of DNA.
News

Gene Therapy Shows Promise for Rare Bone Disease in Mice

Researchers have developed a gene therapy that may provide a long-term treatment for hypophosphatasia. Unlike current therapies requiring frequent injections, this approach delivers a single dose to restore bone mineralization.
A man in brown coat wearing white face mask.
News

COVID-19 Infections Linked to Faulty Proteins in the Brain

Researchers found that COVID-19 is linked to increased biomarkers associated with Alzheimer’s disease, particularly in those hospitalized or with risk factors like high blood pressure.
A diagram illustrating how the research team developed a model of the blood-brain barrier.
News

3D Model Accurately Mimics the Blood–Brain Barrier

A 3D model has been developed that accurately replicates the complex structures of cerebral blood vessels, enabling researchers to mimic the blood–brain barrier.
Cells.
News

Understanding Endosomal Recycling Could Lead to New Disease Therapies

Researchers at UT Southwestern identified how SNX17 and Retriever interact to regulate endosomal recycling, a crucial process for protein transport. Using cryo-EM imaging, they revealed a key binding mechanism.
A 3D model of a human brain.
News

Brain Immune Cells in High-Risk Individuals React Differently to Alcohol

Rutgers researchers discovered that microglia from individuals with a high genetic risk for alcohol use disorder (AUD) are more active after alcohol exposure, pruning more neural connections.
Medication capsules in and to the side of bottle.
News

Targeted Therapy Shows Effectiveness in Skin Disease Patients

Mayo Clinic researchers have identified a targeted therapy that could bring relief to people living with lichen planus, a chronic inflammatory skin condition of the skin, hair, nails, mouth and genitals.
T cells, with cell surface proteins visible.
News

Regulatory Immune Cells Regenerate the Thymus Following Cancer Therapy

Researchers have demonstrated a way to boost thymic function after damage using a specific type of regulatory T cell.
A blue and red capsule split in two.
News

How an Effective Cancer Therapy Was Redesigned To Make It Safer

UIC researchers have redesigned asparaginase, a key leukemia treatment, to reduce severe side effects like liver damage and blood clots. The modified enzyme is more effective and may treat other cancers like melanoma.
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