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The Immune System – News and Features

The 3D structure of the protein BAX, which is involved in cell death.
News

Death-Defying Molecule Could Slow Neurodegenerative Disease Progression

Researchers have identified a small molecule that can selectively block cell death. The findings lay the groundwork for next-generation neuroprotective drugs for degenerative conditions, which currently have no cure or treatments.
Large green parasites "bite" into pink T cells, taking chunks from them and reusing them as a disguise.
News

"Tissue-Dissolving" Parasite Kills Human Cells and Uses Their Proteins as a Disguise

Researcher have discovered that the parasite Entamoeba histolytica bites into human cells and co-opts their proteins as a disguise from the immune system.
Cat nuzzling a dog playfully while lying together on green grass outdoors.
News

Cats Live Longer Than Dogs? Their Brains and Genes May Explain Why

An international study of 46 mammal species shows that larger brains and a more complex immune system are linked to longer lifespans. Researchers found gene family expansions in immune-related genes among long-lived animals.
The monkeypox virus, the target for an existing vaccine used to prevent smallpox.
News

Smallpox Vaccine Shows Promise Against the Monkeypox Virus

Researchers have employed a cross-species immunological analysis to provide new insights into a smallpox vaccine's immunogenicity and safety against the monkeypox virus.
Illustration of cancer cells dividing.
News

Reactivity to Tumor Antigens is Important for TIL Therapy

A team of researchers from Moffitt Cancer Center has found new insight into why some lung cancer patients do not benefit from tumor-infiltrating lymphocyte, or TIL therapy.
Close-up of the tip of a nasal spray, the administration type used in a potential flu vaccine.
News

Nasal Spray Antibody Treatment Protects Mice From Flu

Scientists have engineered a monoclonal antibody that can protect mice from a lethal dose of influenza A, a new study shows. The protective effect was enhanced by delivering the antibody in a nasal spray.
Immunohistochemical staining in mice shows <i>Porphyromonas gingivalis</i> (green) entering cardiac muscle through small blood vessels in the left atrium.
News

The Bacteria in Your Gums Could Be Damaging Your Heart

New research shows that the gum disease bacterium P. gingivalis can slip into the bloodstream and infiltrate the heart. There, it quietly drives scar tissue buildup, disrupting electrical signals and raising the risk of atrial fibrillation.
A white T cell, with complex surface structures.
News

Key Enzyme Prevents Immune Cell Exhaustion

A key enzyme and its molecular pathway are critical to keeping activated CD8+ T cells active and away from “exhaustion”, offering an avenue to bolster the immune response to viruses and cancer.
A doctor prescribing Alzheimer's medication with a bottle of pills and a brain on the desk.
News

People Taking HIV Drugs Are Less Likely To Develop Alzheimer’s

Scientists are calling for clinical trials to test the potential of HIV drugs called NRTIs to prevent Alzheimer’s disease after discovering that patients taking the drugs are substantially less likely to develop the condition.
Human NK cells have large nuclei stained in blue and droplets of fat stores stained in red.
News

Ascites Weakens Immunity in Ovarian Cancer Patients

New research led by Irish scientists has uncovered how lipid-rich fluid in the abdomen, known as ascites, plays a central role in weakening the body’s immune response in advanced ovarian cancer.
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