The Immune System – News and Features

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White Blood Cell Count May Predict COVID-19 Severity
A new study based on Women’s Health Initiative data suggests that a readily available and inexpensive clinical marker of inflammation could be key in predicting debilitating COVID outcomes in postmenopausal women.

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Treatment Boosts Cure Rate for Most Common Form of Breast Cancer in Trial
Adding an immunotherapy drug to the chemotherapy that patients receive ahead of surgery can dramatically improve breast cancer cure rates.

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Method Enables Lab-Grown T Cells To Live Longer and Better Destroy Cancer Cells
Scientists developed a novel method to grow T cells that survive longer and fight cancer more effectively. By altering their metabolism, these lab-grown T cells resisted melanoma for nearly a year in mice, offering new hope for cell therapies.

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Relationship Detail How the Immune System Maintains Food Tolerance
New research identifies specific gut antigen-presenting cells (APCs) that instruct the immune system to tolerate food while defending against infections. The findings reveal immune pathways that shift under parasitic infections.

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AI Tool Predicts T-Cell Epitopes for Accelerated Vaccine Development
MIT and Ragon Institute researchers have developed MUNIS, an AI-driven deep learning tool that predicts CD8+ T cell epitopes with unprecedented accuracy. MUNIS enhances vaccine design for diseases like HIV and influenza.

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How the Maternal X Chromosome Impacts Memory and Aging
A UCSF study reveals that maternal X chromosome expression may accelerate brain aging and cognitive decline. Female mice with silenced paternal X genes showed faster hippocampal aging, but CRISPR reactivation reversed deficits.

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Shared Mechanism Drives Enhancer Region Looping and Activation
New research indicates that the looping and activation of enhancers occurs by a shared genetic mechanism.

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How Plants Mount an Immune Response Revealed
New research has identified crucial components and mechanisms of the plant immune system, potentially helping to develop strategies against pathogens.

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Electrodes Connected to Cells May Help Treat Neurological Diseases
Linköping University researchers have anchored organic electronics to individual cells without genetic modification, enabling precise cell stimulation. Using conductive polymers, it avoids damage from traditional electrodes.

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Giant Clams Have Genomes To Suit Their Algal Partners
Researchers sequenced the genome of the giant clam Tridacna maxima, revealing genetic adaptations for algae symbiosis. These include weakened immune systems to host algae and fewer genes controlling body weight.
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