Therapeutic Delivery – News and Features

A drug developed at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) has been shown to extend survival for patients with glioblastoma, the most common primary brain tumor in adults.

A naturally occurring molecule resembles semaglutide in suppressing appetite and reducing body weight. Notably, animal testing also showed that it worked without some of the side effects of semaglutide.

A new technology from researchers at the California NanoSystems Institute at UCLA is aiming to turn the tables on tumors that migrate from the pancreas to the liver.

Researchers at Mass General Brigham found that a nasal spray delivering anti-CD3 (Foralumab) reduces neuroinflammation, limits central nervous system damage and improves behavioral outcomes in mice with traumatic brain injury.

A method developed by a research group at Tampere University seeks specific molecules that can target desired tissues through the bloodstream and penetrate tissues by passing through cells.

Scientists developed a method to protect cancer patients from radiation damage using a protein from tardigrades. When delivered via mRNA, the protein shields DNA from radiation-induced harm.

Researchers developed a cancer vaccine that uses tumor lysate to enhance immune recognition of solid tumors. The vaccine successfully targets melanoma, breast, lung and ovarian cancers in animal models.

Researchers at Rice University and Vanderbilt University found that combining focused ultrasound (FUS) with TRAIL protein therapy significantly reduces prostate tumor size in lab models. The treatment enhances cancer cell death via Piezo1 activation.

ETH Zurich researchers have revealed how ultrasound-activated microbubbles create liquid jets that pierce blood vessel walls, allowing drugs to enter the brain. Their findings clarify the mechanisms behind microbubble therapy.

Researchers developed Deep Nanometry, a high-speed AI-powered technique that detects rare nanoparticles such as extracellular vesicles (EVs) linked to early-stage cancer. This deep learning-based noise removal method improves sensitivity.