Vaccine Design and Testing – News and Features

Researchers developed the LASSARAB vaccine, using a deactivated rabies virus to protect against Lassa fever. In preclinical trials, it prevented severe disease and death in animals.

Around 300,000 people die from hepatitis C every year. A new study is the first to map the protein complex that enables the virus to infect our cells, potentially paving the way for an effective vaccine.

The monoclonal antibody SC27 effectively neutralizes numerous SARS-CoV-2 variants and related coronaviruses. SC27 targets multiple sites on the spike protein, showing broad protection in lab tests and animal models.

Researchers have discovered an antibody able to neutralize all known variants of SARS-CoV-2, which could better protect the population against current and future variants.

A pilot study identified that stress, BMI, exercise, and hormonal birth control influence COVID-19 vaccine side effects. Notably, exercise impacts side effects differently between doses.

Researchers developed a universal flu vaccine, which analyzed thousands of virus strains to identify conserved proteins. In animal trials, the vaccine elicited a strong immune response and provided protection against multiple flu strains.

Scientists at St. Jude Children’s Research Hospital and Washington University School of Medicine found that T follicular helper cells determine the effectiveness of vaccine-induced immunity against flu.

A team has made a discovery in the fight against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the virus responsible for COVID-19. They have found new insights into how the virus infects human cells and how it can be neutralized.

Highly localized TB strains are less infectious in cosmopolitan cities and more likely to infect people from the geographic area that is the strain’s natural habitat.

Researchers have discovered that highly localized TB strains are less infectious in cosmopolitan cities and more likely to infect people from the geographic area that is the strain’s natural habitat.