CRISPR: Gene Editing and Beyond

Discover how Microsoft Genomics is empowering organizations to explore new avenues of research. The Seattle Children's Hospital SIDS (Sudden Infant Death Syndrome) research with Microsoft Genomics uses Microsoft AI to analyze data in a massive scale. With Microsoft AI, Seattle Children's Hospital is able to identify genetic contributions to pediatric disorders and come closer to reaching their goals of recognizing SIDS earlier and preventing it from happening.

"Stress granules" belong in the cellular toolbox of survival strategies. Proteins and RNA huddle together into membrane-less blobs when the cell is threatened, a mechanism which is also critical for proper maternal mRNA storage, synaptic plasticity, tumor progression and neurodegeneration. These previously invisible basic genetic processes have been captured for the first time, using fluorescence microscopy.

From the smallest single-celled organism to the largest creatures on Earth, every living thing is defined by its genes. With recent advancements, scientists can change an organism’s fundamental features in record time using gene editing tools such as CRISPR. But where did this medical marvel come from and how does it work? Andrea M. Henle examines the science behind this new technology.