We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience, read our Cookie Policy

Why Are Polygenic Risk Scores Important?

Video   Aug 20, 2018 | Shared with permission from the Broad Institute of MIT and Harvard University

 

Polygenic risk scores are are calculated using data from genome-wide association study (GWAS) summary statistics.

In polygenic risk scoring, the number of risk alleles carried by an individual are summed, and weighted by the effect size from the discovery GWAS. 

Using data from 400,000 participants in the UK's Biobank initiative, polygenic risk scoring can be used to help ID those at risk for five deadly diseases, including coronary artery disease and breast cancer.

Sekar Kathiresan explains the place of capturing polygenic risk scores in healthcare and how it can be integrated with other measures of risk.

Speaker: Dr Sekar Kathiresan, Director of the Center for Genomic Medicine, Massachusetts General Hospital and Director of the Cardiovascular Disease Initiative and Institute Member, Broad Institute.

Video credit: the Broad Institute of MIT and Harvard University.

 
More Information
 
 
 

Recommended Videos

PromethION in action, in labs around the world

Video

The PromethION is Oxford Nanopore Technologies' largest sequencing device, capable of delivering many terabases of data, in real time, from a single run. Hear how teams across a broad range of applications, based in labs all over the world — US (UCSF, UCD, JCVI and UCSC), China (GrandOmics and Biomarker) and Europe (KeyGene, Genescope and UMC Utrecht) — are using PromethION in their work.

WATCH NOW

T Cell Actively Killing a Cancer Cell

Video

This incredible live footage shows a T cell actively killing a cancer cell.

WATCH NOW

Flow Cytometry Panel Builder

Video

This online tool guides you through flow cytometry panel design, providing a simplified, customizable experience to fit your flow cytometry panel design needs.

WATCH NOW

 

Like what you just watched? You can find similar content on the communities below.

Cancer Research Diagnostics Informatics

To personalize the content you see on Technology Networks homepage, Log In or Subscribe for Free

LOGIN SUBSCRIBE FOR FREE