Latest On-Demand Webinars

In this webinar, our expert speakers will focus on various gene editing systems and how you can utilize analytical instrumentation to characterize the various components.

We will introduce the National Institutes of Health (NIH) Center for Alzheimer’s and Related Dementias (CARD) long-read sequencing initiative, which will generate a new genetic resource for Alzheimer’s and related dementias from thousands of human brain samples.

bit.bio’s first-of-its-kind precision cellular reprogramming technology, opti-ox™, addresses the limitations of lot consistency, cell definition and scalability by controlling the precise expression of cell-fate determining genetic factors.

RNA dependent RNA polymerase (RdRp), is essential in the RNA replication within the life cycle of the severely acute respiratory coronavirus-2 (SARS-CoV-2), causing the deadly respiratory induced sickness COVID-19.

In this webinar, our expert speaker, Vanessa Porter, will present her research into identifying and classifying genomic perturbations arising from HPV integration.

Traditional organoid culture can present challenges for the downstream analysis of single organoids. In this webinar, Dr. Allysa Stern will discuss a unique workflow that enables clonal organoid development, monitoring of iPSC differentiation over time and automated isolation of single organoids.

Dr. Scott Magness will then present a case related to his group’s work investigating tumor cell heterogeneity through clonal organoid morphology and transcriptomics. He will discuss new approaches using single organoid transcriptomics to evaluate organoids derived from single cells from gastric dysplastic tissues and how this approach might reveal new ways to investigate tumor cell heterogeneity and evasion of some cells from cancer treatments.

The field of synthetic biology revolves around the design-build-test-learn (DBTL) cycle, where biological components are adjusted in multiple iterations.

CRISPR/Cas9, a ground-breaking tool for altering genes with the potential to fully cure genetic diseases, has made its way into the clinic, accelerating research on new therapies using this technology.

As a cornerstone of genetic analysis in biological research, quantitative PCR (qPCR) and digital PCR (dPCR) are the most sensitive molecular methods to analyze nucleic acids and play a key role in the development of cell and gene therapies (CGT).

These tools are widely used during CGT development for example in biodistribution, pharmacokinetics and pharmacodynamics of the investigational lead molecule. But many samples, including tissues rich in nucleases, lipids and other inhibiting substances and target molecules that are short or contain modified bases, can be challenging to work with. For these types of samples, assay design using advanced strategies, concentration standards, spike-in controls and validated normalization is key for reliable analyses.

In this webinar, Dr. Kubista will present strategies for implementing reliable qPCR and dPCR analysis in CGT development while highlighting best practices for adhering to MIQE and dMIQE guidelines and the recently released ISO standard, ISO 20395:2019.

Speaking at the Vaccine Research & Development 2022, Kyle Luttgeharm, PhD, Product Manager from Agilent presented their talk on IVT RNA production and
accurate and precise mRNA analysis.