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Genomic Atlas of the Human Proteome and Neurological Disorders
Webinar

Genomic Atlas of the Human Proteome and Neurological Disorders

Genomic Atlas of the Human Proteome and Neurological Disorders
Webinar

Genomic Atlas of the Human Proteome and Neurological Disorders

Carlos Cruchaga
Carlos Cruchaga
B. Burton & R.M. Morriss III Professor of Psychiatry, Neurogenomics and Informatics Center Director, Washington University School of Medicine

Understanding the tissue-specific genetic architecture of protein levels is instrumental to understand the biology of health and disease.

Here, we present the first multi-tissue study yielding hundreds of novel protein quantitative loci (pQTLs). This data will be instrumental to identify the functional gene from genome-wide association study (GWAS) signals, identify novel biological protein-protein interactions, identify novel potential biomarkers and drug targets for complex traits.

Attend this webinar to learn about:

  • A multi-tissue study which yielded hundreds of novel protein quantitative loci (pQTLs) in brain tissue, cerebrospinal fluid (CSF) and plasma from participants with and without Alzheimer's disease.
  • The use of these pQTLs in the identification of risk genes from GWAS data.
  • Potential drug targets for neurological diseases including Alzheimer’s disease.
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