lncRNAs Advancing Therapeutics for Cancer and Heart Disease
The authors of two new high impact papers describe their work on long non-coding RNAs.
Prof. Marine from KU Leuven in Belgium presents the recent Nature paper: Melanoma cancer cells are addicted to the lncRNA SAMMSON. They show that Antisense LNA™ GapmeRs targeting SAMMSON significantly suppress tumor growth.
Prof. Thum from Hannover Medical School in Germany describes the recent Science Translational Medicine paper demonstrating that silencing the lncRNA Chast reverses cardiac disease.