GMP Ancillary Materials for Cell and Gene Therapy Manufacturing
Ancillary materials (AMs), also called raw materials in Europe, are components, reagents, and materials used in the manufacturing of cell, gene, and tissue-engineered (CGT) therapies but are not intended to be present in the final product formulation.
A Successful Journey to Cell Therapy Manufacturing: From Research and Development to Lot-Release
Cell therapy is a transformative cancer treatment that utilizes genetically modified cells from a healthy donor or patient's own immune system to attack cancer cells, but manufacturing these cells represents a major challenge for the industry.
Racing Against Time: Rapid, High-Throughput Discovery of Antibody Therapeutics for SARS-CoV-2
Vanderbilt University Medical Center researchers Robert Carnahan and Pavlo Gilchuk are attempting to compress the timeline for therapeutic antibody development, by integrating a series of advances in single-cell messenger RNA sequence analysis, bioinformatics, synthetic biology and high-throughput functional analysis.
Channelopathies Resolved via Cryo-EM and X-Ray Crystallography
Attend this webinar to learn how Dr. Filip Van Petege's lab is solving crystal structures of isolated RyR domains in wild type and disease mutant forms, exploring excessive phosphorylation of RyRs as well as investigating the mechanical coupling between CaV1.1 and RyR1 in skeletal muscle.
New, Rapid Sequencing Tools for Poliovirus Surveillance
In this webinar, Dr Alex Shaw will highlight how nanopore sequencing-based methods for the detection of the virus in both stool and sewage can provide additional tools to rapidly identify poliovirus cases and discover silent transmission of the virus in populations.
Using In Vitro Approaches To Investigate Idiosyncratic Drug-Induced Liver Injury
This talk will describe using a combined experimental approach of gene expression profiling, exosome analysis, and high-content imaging in 2D and 3D liver cell culture models to evaluate early IDILI events and risk factors contributing to overt liver injury observed in the clinic.