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Antigenic Drift vs Antigenic Shift

Article

As part of the host-pathogen arms race, viruses are continually evolving to evade the host immune response, be it from previous infection or immunity acquired through vaccination. Here we take a look at the processes of antigenic drift and antigenic shift.

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CellStream™ Benchtop Flow Cytometer for Sensitive Cell Analysis

Video

The new CellStream™ benchtop flow cytometer delivers unparalleled sensitivity and flexibility for cell and particle analysis.

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Developing an HIV Vaccine

Video

Professor Robin Weiss and Dr Laura McCoy explain some of the processes and challenges involved in developing an HIV vaccine.

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Care in the Community – How Biofilms Improve Bacterial Survival

Article

A single bacterial cell on its own is vulnerable to attack and like many living things they can benefit from safety in numbers. But bacteria take communal living to a whole new level, forming veritable civilizations - the bacterial biofilm.

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Rooting in the Genomes of Giants

Rooting in the Genomes of Giants

News

Giant virus genomes have been discovered for the first time in a forest soil ecosystem.

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Making AI Less Biased
News

With machine learning systems now being used to determine everything from stock prices to medical diagnoses, it's never been more important to look at how they arrive at decisions. A new approach out of MIT demonstrates that the main culprit is not just the algorithms themselves, but how the data itself is collected.

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Fighting the Good Fight
News

Blocking an important enzyme in staphylococcal metabolism in a targeted manner would allow the pathogens to be starved.

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Inflammation-blocking Inhibitor Could Treat Sepsis Too
News

A new inhibitor which decreases lung inflammation could hold the key to treating Acute Respiratory Distress Syndrome and sepsis.

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Emerging Classes of Next-generation Biotherapeutics
Emerging Classes of Next-generation Biotherapeutics
Article

We are entering uncharted territory in biopharmaceutical development. Emerging new classes of treatments are harnessing the natural power of viruses and cells and engineering them to fight human diseases. As our arsenal of conventional therapies begins to fail, a new army of biotherapeutics is on the horizon. Here, we look at two new classes of treatments leading the charge.

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Through the Looking Glass of Single Cell Proteomics
Through the Looking Glass of Single Cell Proteomics
Article

To pick apart the differences between individual cells in complex multicellular organisms, we need to look at cells one-by-one. This article takes a look at how several scientists in North America are using single cell proteomics (SCP) technologies to discern disease pathogenesis and enhance directed stem-cell differentiation.

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Understanding the Lytic Cycle – What Are the Steps?
Understanding the Lytic Cycle – What Are the Steps?
Article

Bacteriophage (phage) are viruses that specifically infect bacteria. They have a two-phase lifecycle, residing in a dormant state within the host genome (lysogenic cycle) or hijacking the host cellular machinery for their own replication (lytic cycle). Here we will explore the important steps of the lytic cycle.

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Cold Plasma for Seed, Fruit and Vegetable Decontamination and Plant Disease Control
Cold Plasma for Seed, Fruit and Vegetable Decontamination and Plant Disease Control
Article

An effective way to increase crop yield is to minimize losses to pathogenic microorganisms by improving the disease resistance of crop plants. A recently emerging alternative to conventional methods for improving plant disease resistance is cold plasma.

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Chemical Snapshots and Molecular Maps with Mass Spec Imaging
Chemical Snapshots and Molecular Maps with Mass Spec Imaging
Article

Mass spectrometry imaging (MSI) is a powerful tool increasingly being used in many fields including cancer research, biomarker discovery and drug development. This article explains why MSI is the technique of choice in many labs, discusses its use in research, and covers how some inherent challenges are being addressed.

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MALDI Imaging Mass Spectrometry (MALDI IMS): A Marriage of Mass Spectrometry and Morphological Spatial Resolution
MALDI Imaging Mass Spectrometry (MALDI IMS): A Marriage of Mass Spectrometry and Morphological Spatial Resolution
Article

Matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI IMS) is a powerful analytical technique that enjoys the sensitivity of mass spectrometry coupled with spatial distribution information.

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