Latest Application Notes
Where Do We Go From Here: A Reflection of COVID-19
Download this app note to explore various solutions designed to improve COVID-19 detection and the development of vaccines and therapeutics.
Studying the Molecular Mechanism of Viral Replication in Real Time
Download this app note to discover a fluorescent-based approach that can enable real-time measurement of viral gene expression and be used to study virtually any virus in a 96- or 384- well format.
Enhancing the Therapeutic Properties of a Cancer-Targeting Affibody by Soft Mutagenesis
Affibodies are synthetic antigen-binding proteins. They offer many advantages over monoclonal antibodies, including smaller sizes, enhanced thermal stability and rapid refolding capability. These advantages make affibodies an attractive platform for the development of therapeutics, diagnostics and bioimaging technology.
Tiling Across Viral Genomes to Investigate Immune Escape
Viruses exploit high-dimensional RNA structures to facilitate viral replication and impede host restriction. Here, a novel next-generation sequencing (NGS)-based screening workflow, called Fate-seq, was used to define and characterize high-dimensional RNA structures.
Convenient Customization of Your Cation Exchange Analysis
Therapeutic monoclonal antibodies (mAbs) are highly heterogeneous molecules due to being composed of a large number of variants. When the variants are present in the pharmaceutical protein, it is possible their biological activity could be altered.
Benefits of an Ergonomic and Electronic Pipette for RT-PCR
Pipetting ergonomics has emerged as an important consideration in the research laboratory, especially during the past year when diagnostic laboratories were forced to work for long hours due to the global SARS-CoV-2 pandemic.
Rapid Quantitative Analysis of Fermentation Broth Samples
Download this app note to discover a system that achieves high throughput for screening and requires minimal sample preparation.
Ultrapure Water in Cell Cultivation
Water is a major component of all cell culture media and is, therefore, needed to prepare media, buffers and additives, as well as to serve many ancillary functions, such as heating, cooling, cleaning and rinsing.
Preventing Cell Death
Download this app note to discover a system that can be used for product formulation, diafiltration solutions as well as extraction, rinsing and sanitization steps.
Predicting Drug Permeability With a Gut Microphysiological System
Download this app note to discover a gut MPS that has physiologically relevant morphology, reduced barrier integrity and mucus expression. It can be used to predict drug permeability across an intestinal barrier.