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Latest Application Notes

Application Note

Improved GPCR Engineering With Synthetic Site Saturation Variant Libraries

Download this app note to learn more about how saturation mutagenesis can be used to identify functional GPCR variants, why error-prone PCR results in low variant representation as well as the advantages of synthetic saturation mutagenesis libraries.
Application Note

Recent Developments in Covid Virology

COVID-19 is caused by the SARS-CoV-2 virus. While some patients have mild or asymptomatic illness, for others it can be fatal. Understanding the immune response to SARS-CoV-2 at a molecular level is useful for the development of effective vaccines, treatments and prognostic tests.
Application Note

Accurately Analyze Fluorescent Widefield Images

The specificity of fluorescence microscopy allows researchers to accurately observe and analyze biological processes and structures quickly and easily, even when using thick or large samples. However, out-of-focus fluorescence increases background, reduces contrast and makes accurate image segmentation more challenging.
Application Note

Pushing the Boundaries of High Sensitivity Epigenetic Applications

Download this free application focus to learn more about innovative next-generation methylation detection systems.
Application Note

Microbubbles Offer a Versatile, Flexible Platform for Targeted Capture of Diverse Analytes

Download this app note to discover a solution that can be used with any biotinylated affinity molecule, enables floatation-based separation of diverse targets as well as provides workflows that are exceptionally gentle on delicate analytes.
Application Note

The Development of a Sensitive and Reliable qRT-PCR-Based SARS-CoV-2 Wastewater Analysis Protocol

Wastewater testing offers valuable insight on community-level data for various analytes, including pathogens that are associated with infectious diseases. Quantitative reverse transcriptase PCR (qRT-PCR) is well suited for wastewater analyses of pathogens due to its sensitivity, scalability and cost-effectiveness.
Application Note

Optimize Cell and Gene Therapies With Single-Cell Multiomics

One of the more promising types of cancer immunotherapy involves engineering immune cells to recognize and attack cancer.
Application Note

Complete PCR-Based Detection Workflow of SARS-CoV-2 in Wastewater

Download this app note to discover a workflow that can detect SARS-CoV-2 RNA from challenging sample matrices and be used for the extraction and detection of other pathogens.
Application Note

Mannose Glycans Content Screening for Human-mAb Samples

Glycosylation refers to the formation of linkages with glycosyl groups, covalently attaching a carbohydrate to another molecule. Antibody glycosylation is critical due to the role carbohydrates play in modulating effector functions which affect safety and efficacy of therapeutic antibodies.
Application Note

Transforming Drug Discovery Through Precision Research

The high resolution and scale that single cell analysis provides is revolutionizing drug discovery and development by introducing comparative, longitudinal and causal information that transforms our ability to understand biology and disease.
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