Latest Application Notes

Antibody-based derivatives have received increased attention as therapeutics in biopharmaceutical development because of their unique capacity to engage multiple molecular targets, engage immune effector cells or even penetrate tissues previously inaccessible to conventional mAbs.

The SARS-CoV-2 spike protein has rightly garnered attention as a leading candidate for protein-based vaccines for COVID-19. Multiple studies have shown that neutralizing antibodies bind to the spike protein at both peptide and peptidoglycan epitopes.

The threat of global pandemics emphasises the quick identification of the cause of an emerging disease and its route of infection. Once these characteristics are defined, drug repurposing offers to identify previously approved drugs that might be applicable and quickly approvable for the treatment of the new disease.

Download this app note to discover a novel system that enables rapid clarification of mammalian cell cultures without the need for centrifugation and has no impact on product quality.

Traditional methods of immune surveillance allow researchers to interrogate one data type at a time, leaving them with an incomplete understanding of the immune response. In order to characterize the immune response, the ability to phenotype individual cells with multiple parameters and at massive scale is necessary.

Studying the SARS-CoV-2 genome can provide valuable insights into its evolution and transmission, as well as aiding surveillance and vaccine development efforts to help control the COVID-19 pandemic. Download this app note to discover an RNA sequencing approach that can accurately identify low copy number viral pathogens.

As COVID-19 enters the normal phase of prevention and control, whole genome information for SARS-CoV-2 is required to analyse the virus. Download this app note to discover a detection solution that provides a fast, simple and streamlined workflow.

Download this app note to discover a novel virus discovery and surveillance approach that provides high sensitivity detection of known viral species whilst delivering enrichment and complete characterization of novel viral sequences.

Download this app note to learn how RT-LAMP assays can increase diagnostic capacity, detect RNA amplification in real-time, be performed under isothermal conditions and be used to test samples in under 40 minutes.

Download this application compendium to discover an ultra-high performance liquid chromatography approach for refined charge variant analysis of mAbs, elevated mAb aggregate analysis and HIC analysis of drug-to-antibody ratio with high salt concentrations.