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A Highly Sensitive Solution for the Quantification of Cyclic Peptides

A Highly Sensitive Solution for the Quantification of Cyclic Peptides
Credit : Istock

Due to their structural stability and conformational rigidity, cyclic peptides have emerged as successful therapeutic candidates for different conditions, including cardiovascular diseases.

However, current bioanalytical methods for the quantification of cyclic peptides in biological matrices remain challenging. Moreover, traditional LC-MS-based methods also lack the sensitivity to efficiently quantify these compounds.

This application note presents a highly sensitive quantification workflow for cyclic peptides using accurate mass spectrometry.

Download this application note to discover: 

  • A simple MS workflow for cyclic peptide quantification 
  • A method for low-level quantification of cyclic peptides with exceptional linearity, precision and accuracy
  • A single platform for streamlined data acquisition, processing and management
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