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Data Reproducibility for the Development of Safer Gene Therapies

Data reproducibility for safer gene therapy

Immunogenicity is a key consideration in the development of safe gene therapy products. In fact, certain product components can cause unintended immune responses with life-threatening implications if not addressed.

Reproducible quantitation of gene expression can help researchers investigate potential sources of vector-induced immunotoxicity. Hence, data reproducibility is a cornerstone of safe therapeutic development.

This application note highlights a robust and reliable qPCR-based approach to reproducible data generation with significant insights for vector design.

Download this application note to discover:

  • Potential sources of immunotoxicity in  gene therapy products
  • How gene expression data can inform vector design 
  • Ways to minimize experimental error and support data concordance

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