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Fast and Reliable Method for Bacterial Artificial Chromosome Analysis

Bacterial Artificial Chromosome Analysis
Credit: iStock

Bacterial artificial chromosomes (BACs) are a useful molecular biology tool in gene expression studies. However, their large size (100–300kb) renders electrophoretic separation by pulsed field gel electrophoresis (PFGE) a challenge, thus causing bottlenecks at critical quality control steps.

Choosing the right fragment separation method, optimized for high-molecular weight samples, can significantly optimize BAC workflows. It can reduce electrophoresis time from up to 26 hours to under 3 hours. 

This application note highlights the latest pulse system technology for quick and easy BAC analysis. 

Download this app note to discover: 

  • The latest in pulse field electrophoresis technology
  • A preoptimized method for quick and easy large fragment separation 
  • An automated electrophoresis system for better objective insights 


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