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Studying the Molecular Mechanism of Viral Replication in Real Time

Viruses are obligate intracellular pathogens that can infect all living organisms. The current global pandemic, as a result of SARS-CoV-2, is a perfect example of how detrimental a virus can be not only to human health but also economically. Viruses interact and hijack host cellular machineries to allow them to replicate and spread. A clear understanding of these host–virus interactions is crucial to uncover the molecular mechanisms underpinning infection and to enable the development of new treatments.

Download this app note to discover a fluorescent-based approach that can:

  • Enable real-time measurement of viral gene expression
  • Be used to study virtually any virus in a 96- or 384- well format
  • Achieve high reproducibility and sensitivity, making it suitable for genetic and drug screens