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Latest Articles

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Understanding the Mechanisms of Streptococcal Infection and Disease

Professor Shiranee Sriskandan is a Clinical Professor of Infectious Diseases at Imperial College London. She leads a team focused on the mechanisms by which streptococcal infections cause serious disease. As well as her research work, Professor Sriskandan undertakes teaching within the University and is also a medic at Hammersmith Hospital.
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How Are We Developing Vaccines for the Future?

This article highlights the types of vaccine, trends in developing future vaccines and discusses new delivery methods and strategies to help advance our understanding of the immune system.
Article

Novel Collagen Membrane Improves Colon-on-a-Chip Functionality

A microfluidic model of the colon has been built using natural tissue base matrix, which closely mimics the structure and function of the colon.
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Metagenomics: Exploring Microbiomes at Nature’s New Frontiers

Advances in sequencing technologies are providing scientists with a powerful way to view microbial communities in unprecedented detail. Metagenomics is a rapidly evolving field that is uncovering a wealth of hidden biodiversity, revolutionizing our understanding of uncharted corners in the living world.
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Exploiting the Tumor Microenvironment for Cancer Therapeutics

It’s more than a century since Paget first proposed the ‘soil and seed’ hypothesis in cancer, providing evidence that the environment surrounding a tumor is as important as the tumor itself. Research in this area has gathered momentum and it’s now the focus of intense research efforts.
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Sensitive Quantification of Drug Metabolites Using LC-MS

Determining what happens to a drug after it enters the body is a key consideration in the drug development process. Liquid chromatography coupled with mass spectrometry (LC-MS) has emerged as one of the most powerful analytical tools for the screening and identification of drug metabolites. Advances in the field of LC-MS have allowed scientists to analyze drug metabolic pathways and drug-drug interactions more closely, and improve therapeutic strategies for many challenging diseases.
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Tech Solutions for Drinking Water Analysis

Improved access to clean and safe drinking water is key for health and survival and has been classified as a human right. Here, we take a look at some of the novel solutions, both hi-tech and low-tech, that scientists are designing to help monitor drinking water source safety.
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New Tools for Combating Antibiotic Resistance

Antibiotic resistance is a serious health problem, causing illnesses that were once easily treatable with antibiotics to morph into dangerous infections, leading to serious disability or even death. To help fight this growing threat, diagnostics companies are developing new tools and techniques that are playing a crucial role in quickly identifying infectious organisms and preventing the inappropriate use of antibiotics.
A printer outputting RNA bases from an RNA sequence.
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RNA-Seq: Basics, Applications and Protocol

RNA-seq (RNA-sequencing) is a technique that can examine the quantity and sequences of RNA in a sample using next-generation sequencing (NGS). Here, we look at why RNA-seq is useful, how the technique works, a basic protocol that is commonly used today and challenges that remain.
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The Future for PCR Diagnostics

The Nobel Prize winning polymerase chain reaction (PCR) technique revolutionized molecular biology on its invention in 1986 and it has done the same for medical diagnostics over the last 15 years. Being able to copy and multiply specific target DNA molecules has opened the door to diagnosing diseases across multiple areas quickly, accurately, and as time progresses at lower cost.
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