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Advances in Monoclonal Antibody Purification and Analysis

Credit: Thermo Fisher Scientific

As the scientific understanding of traditional monoclonal antibody (mAb) therapeutics has advanced, researchers are now engineering proteins to create next-generation antibody modalities including antibody fragments, bispecific antibodies, antibody–drug conjugates and Fc-fusion scaffolds.

These innovations are accompanied by advances in the biotechnologies designed to develop and manufacture them. However, each biomanufacturing process must ensure product purity and efficacy, among other quality criteria, in order to be approved for clinical use. 

This eBook addresses common mAb purification, analysis and quality evaluation challenges and offers solutions for improving process efficiency and reliability.

Download this eBook to explore:

  • Affinity purification in monoclonal antibody manufacturing
  • Process analytics to ensure quality and safety
  • Innovative uses of single-domain antibodies in mAb therapeutic research and development
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