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Scientists at Pall Life Science assessed the relative merits of Protein A HPLC and Protein A biolayer interferometry (BLI) to determine concentrations of monoclonal antibodies (mAb) in a complex feedstock. The results illustrated that the Octet® BLI system provides a fast, accurate and economical means of quantifying mAbs, and decreases process development efforts.

Sino Biological has developed a panel of high-quality recombinant GDNF, NGF, and BDNF to support the research for neurodegenerative diseases.

Interleukin-18 (IL-18) is a pleiotropic pro-inflammatory cytokine. It belongs to the IL-1 superfamily and participates in innate and acquired immunity. Recent studies have implicated the IL-18 pathway in autoimmune diseases, metabolic disorders, and cancers.IL-21: A Modulator in Allergy, Cancer, and Viral Infections

Glial cell line-derived neurotrophic factor (GDNF) plays a vital role in promoting motor neuron survival and axon outgrowth. It is being evaluated in clinical trials as a potential therapeutic for Parkinson’s disease. GFL-like drugs are also being developed to treat disorders such as neuropathic pain and addiction.

Bio-Techne multiplexing tools provide fast, dependable, and highly accurate results with minimal sample waste. Our multiplexing tools offer high throughput testing solutions for timely and reliable research. A large variety of species and analytes will ensure these reproducible and cost-effective assays produce the highest quality results while saving you time. With laboratory applications including biomarker detection and validation, Bio-Techne multiplexing assays are sure to enhance your research.

Octet® BLI platforms are helping accelerate research on Coronavirus by providing:

High-throughput kinetic interaction analysis solutions to rapidly select and characterize vaccine and therapeutic candidates

Efficient workflows for vaccine and biotherapeutic development research

Fast and flexible platform 

Versatile solutions in upstream and downstream vaccine development

Sino Biological has newly launched a number of recombinant cytokines, including IL21, TNF-alpha, and IL-1 beta.

Sino Biological has developed a panel of high-quality recombinant cytokines and receptor proteins as well as antibodies to support the study.

The Omicron (B.1.1.529) strain is by far the most divergent SARS-CoV-2 variant. It is critical to re-evaluate the effectiveness of the current diagnostics and therapeutics against this new variant. Sino Biological has developed recombinant Omicron Spike and Nucleocapsid proteins and validated all available antibodies against the Omicron proteins.

A range of microscope objectives are available and the optimal choice for a given sample and application will depend on several technical factors. Prices can vary from a few hundred dollars to several thousand and in many cases is a real consideration as well. By an understanding of the factors that influence image quality (contrast, signal-to-noise, resolution, etc.), as well as the terms that describe objective classes and types, well-informed decisions can be made and data appropriate for the purpose of the experiment more easily generated.

New, Bright, Fluorescent Nanoparticles Developed for Flow Cytometry. Bio-Rad has now launched ten StarBright Dyes, including StarBright Blue 700, eight StarBright Violet Dyes, and the latest in the range StarBright UltraViolet 400, with many more due to be launched over the coming year.