CD47: Regulation of cellular phagocytosis in cancer, inflammation & neurobiology
Infographic Oct 11, 2017
CD47 is a cell surface ‘don’t eat me’ signal that has been shown to be important in detection and evasion of cancer cells, inflammation, neuronal pruning and other pathophysiological processes.
Blocking CD47 allows tumor cells to be recognized by phagocytes and this cell-cell interaction initiates a cascade of events resulting in tumor cell destruction. As such CD47 is an attractive target for the development of novel therapeutics.
Download this Infographic for an overview of the dynamics of CD47 signaling in the regulation of cancer, inflammation and neuronal pruning and methods to target this pathway for potential immunotherapies.
Air Quality MonitoringInfographic
The quality of the air we breathe is of concern to many, as are the negative impacts that pollutants can have on health in the short term and the lasting effects. Many of us have the potential to come into contact with air contaminants in our day to day lives, so it is vital that efficient monitoring measures are in place to keep us from harm.READ MORE