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How Exactly Do Antibiotics Stop Bacterial Growth?
High-performance microscopy has thrown light on the mechanisms behind how antibiotics stop bacterial growth.
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Enabling Adeno-Associated Virus-Based Gene Therapies
The use of a monoclonal antibody that reduced circulating IgG levels, led to a decrease in preexisting neutralizing antibodies (NAbs) to adeno-associated virus (AAV).
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Drug With Potential To Ease Pain in Osteoarthritis Moves to Clinical Trial
Results from an animal study published in Science Translational Medicine demonstrate that a drug compound can disrupt overactivation of inflammation and manage pain and stiffness in osteoarthritis. The drug will be tested in upcoming Phase I and IIa clinical trials.
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New Drug Candidate Identified Against Mpox
A new drug candidate – nitroxoline – for treating mpox has been identified, with clinical trials due to begin soon.
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What Does Your Microbiome Say About Your Fitness?
According to research, physical activity of moderate duration (over 2.5 hours per week) increased both the richness and diversity of the gut microbiomes compared to study participants that exercised less.
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Peering Into the Complexities of Life on a Leaf
Understanding the interactions between plants and the microorganisms that live on their surfaces may help us develop agricultural management practices that can increase crop productivity and resilience.
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Immune Signals in the Brain Could Lead to Addiction Vulnerability
Researchers have identified brain signals, traditionally associated with inflammation, that contribute to people’s vulnerability to addiction.
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New Intracellular "Smoke Detector" Discovered
Researchers have discovered a new intracellular "smoke detector." The sensor warns of damage to the mitochondria, and if it does not function properly, chronic skin diseases can result.
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