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Genetic Engineering Reveals Evolutionary Pathways
A new study employs genetic techniques to model ancient ancestors of modern-day organisms, enabling researchers to systematically experiment on different versions of bacteria and reveal possible evolutionary pathways.
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Viroids and Viroid-Like Agent Diversity Revealed
The diversity of viroid and viroid-like circular RNAs across species has been revealed by metatranscriptome analysis.
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Origins and Transmission Patterns of Seattle Shigella Outbreak
A genomic study of a sustained, multidrug-resistant Shigellosis outbreak in Seattle enabled scientists to retrace its origin and spread.
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CNS Acts as a Reservoir for Dormant HIV
New research has identified that a layer of CD4+ T cells around the central nervous system acts as a reservoir for HIV during antiviral therapy, enabling a "rebound" of the virus when the treatment is stopped.
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High-Resolution Cellular Map of Crohn’s Disease Created
The atlas is the largest study of single cells from Crohn’s patients to date, and contains the gene expression profiles of more than 700,000 cells from 71 healthy individuals and patients in varying states of inflammation.
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Immunotherapy Success for Sarcoma Patients Linked to the Tumor Microbiome
The tumor microbiome can influence the success of immunotherapy in sarcoma patients, reports new research from UC Davis Comprehensive Cancer Center.
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Enhancing Our Brain's Ability To Fight Disease With CRISPR-Edited Immune Cells
Editing healthy immune cells with CRISPR safely thwarts the brain's resistance to them, helping researchers to harness immune cell function to treat neurological conditions.
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Coffee With Milk May Confer Anti-Inflammatory Benefits
Can something as simple as a cup of coffee with milk have an anti-inflammatory effect in humans? Apparently so, according to a new study. A combination of proteins and antioxidants doubles the anti-inflammatory properties in immune cells.
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Infectious Disease Spread Model Improves Future Case Predictions
An infectious disease model that takes into account age-specific contact patterns whilst applying a common modeling approach has been shown to improve predictions of disease spread.
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Vaccine Against Marburg Virus Shows Promise in Human Study
A newly published paper shows that an experimental vaccine against Marburg virus (MARV) was safe and induced an immune response in a small, first-in-human clinical trial.
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