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Novel Circovirus Discovered and Linked to Hepatitis

A novel circovirus – a small, highly resistant DNA virus – has been discovered and linked to hepatitis in a case study of a patient in Europe.
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Deer Carry SARS-CoV-2 Variants That No Longer Exist in Humans

White-tailed deer ­– the most abundant large mammal in North America – are harboring SARS-CoV-2 variants that once widely circulated but are no longer found in humans.
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New Design Principles To Improve Cancer Vaccines

New vaccine design principles that are based on adjusting the structural location of an adjuvant and the antigen on a nanoscale vaccine have been shown to greatly increase cancer vaccine performance.
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Genetic Engineering Reveals Evolutionary Pathways

A new study employs genetic techniques to model ancient ancestors of modern-day organisms, enabling researchers to systematically experiment on different versions of bacteria and reveal possible evolutionary pathways.
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Viroids and Viroid-Like Agent Diversity Revealed

The diversity of viroid and viroid-like circular RNAs across species has been revealed by metatranscriptome analysis.
Shigella colonies on a chromagar plate culture medium.
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Origins and Transmission Patterns of Seattle Shigella Outbreak

A genomic study of a sustained, multidrug-resistant Shigellosis outbreak in Seattle enabled scientists to retrace its origin and spread.
Small yellow-colored virus particles infecting a large, textured blue-colored cell.
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CNS Acts as a Reservoir for Dormant HIV

New research has identified that a layer of CD4+ T cells around the central nervous system acts as a reservoir for HIV during antiviral therapy, enabling a "rebound" of the virus when the treatment is stopped.
Graphical representation of the human small and large intestines.
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High-Resolution Cellular Map of Crohn’s Disease Created

The atlas is the largest study of single cells from Crohn’s patients to date, and contains the gene expression profiles of more than 700,000 cells from 71 healthy individuals and patients in varying states of inflammation.
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Immunotherapy Success for Sarcoma Patients Linked to the Tumor Microbiome

The tumor microbiome can influence the success of immunotherapy in sarcoma patients, reports new research from UC Davis Comprehensive Cancer Center.
A plastic model of a brain and a brain cell.
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Enhancing Our Brain's Ability To Fight Disease With CRISPR-Edited Immune Cells

Editing healthy immune cells with CRISPR safely thwarts the brain's resistance to them, helping researchers to harness immune cell function to treat neurological conditions.
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