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Why Do Some Vaccines Create Long-Lived Responses and Others Don’t?

A research team has shown in real time how long-lived plasma cells are stored in the bone marrow at around one single cell per hour for several weeks after immunization.
A skyline with smoke coming from chimneys.
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Long-Term Exposure to Air Pollution Undermines the Immune System

Inhaled pollutants can collect in the lymph nodes associated with the lung, accumulating over decades and weakening the immune cells' ability to fight off lung infections.
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HIV Infection Leaves a "Memory" in Cells

New study reveals why comorbidities persist in people living with HIV, despite suppressing the virus through treatment.
Coral seen from underwater. A few different species of fish can be seen.
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Disease-Resistant Corals Can Help “Rescue” Vulnerable Ones

According to a study, disease-resistant corals can help “rescue” corals that are more vulnerable to disease.
A hitchhiker on the side of a road.
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Using CRISPR To Direct Genetic “Hitchhikers”

A new method of using CRISPR-directed transposons to rewrite the genetics of E. coli has been developed by researchers at North Carolina State University.
A picture of a flower from the coca plant.
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Last Steps in the Biosynthesis Pathway of Tropane Alkaloids Identified

Researchers used a yeast-based synthetic biology platform to elucidate the last remaining enzymatic steps involved in tropane alkaloid formation in Erythroxylum coca.
Human small and large intestines.
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Intestinal Microorganisms Influence White Blood Cell Levels in Blood

Intestinal bacteria composition is crucial to driving the recovery of neutrophil counts in the blood of mice following treatments such as stem cell transplants or chemotherapy.
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Restoring the Gut Walls Could Help Save Brain Function After Stroke

Pioneering research has identified a connection between stroke-induced gut leakiness and cognitive impairment and has investigated whether restoring the gut walls could save brain function.
A digitally-colorized transmission electron microscopic image of Zika virus grown in LLC-MK2 culture cells. Virus particles can be seen in blue.
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“Unusual” Antibody Neutralizes Zika Virus Even at Miniscule Levels

Researchers have identified an "unusual" type of antibody that can neutralize the Zika virus, rendering it undetectable in preclinical models.
A vaccine vial and syringe on a blue background.
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“DNA Virus Vaccine” Created To Fight DNA Viruses

Researchers at Rutgers University have developed a novel method for vaccinating against DNA viruses – by creating a replication-deficient version of the live virus that stimulates an immune response.
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