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New Antibiotic Candidate Fights Off Over 300 Drug-Resistant Bacteria
Researchers report a new molecule that inhibits drug-resistant bacteria in lab experiments, as well as in mice with pneumonia and urinary tract infections, which could one day be used to treat challenging infections in humans.
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Mystery “Jumping” Gene Helps Mice Survive Infections
A transposable element or "jumping" gene in mice has been shown to control the immune system in response to viral infection, promoting host survival.
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How Bacteria Defuse the Innate Immune System's Antimicrobial Weaponry
How do a wide variety of bacteria — both pathogenic and commensal — survive antimicrobials released by the mammalian innate immune system?
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Monkeypox Added to Wastewater Screening Panel
An ongoing program that monitors wastewater for the presence of SARS-CoV-2 and has effectively predicted subsequent surges in COVID-19 cases in San Diego has been expanded to detect the presence of monkeypox.
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Microbiome Molecule Can Induce Neuronal Inflammation
Research reports for the first time a pathway that begins in the gut and ends with a potent pro-inflammatory toxin in brain cells contributing to the development of Alzheimer’s disease (AD).
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Next-Generation Sequencing Compared to Standard of Care Diagnostics
According to a study, next-generation sequencing diagnostic systems enable clinicians to simultaneously sequence multiple strands of DNA found in patient samples and use that analysis to identify a single pathogen.
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BCG Vaccine Prevents TB in Young Children, but Adults May Need Additional Protection
The tuberculosis (TB) vaccine, bacille Calmette-Guérin (BCG), is one of the most widely administered vaccines across the globe. Nearly 100 years old, it is the only vaccine ever administered to treat TB, which afflicts more than 10 million people each year.
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"Molecular Tool" Could Trigger Targeted Immune Responses
A small molecule has been designed that can be used as a molecular tool to trigger immunogenic cell death, enabling researchers to better understand the effects of damage-associated molecular patterns in immunity.
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Microbes Transported Around the Globe in Drought-Induced Dust
Research shows that higher concentrations of microbe-carrying dust are landing at lower elevations, where people are more likely to be hiking.
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New Molecule Could Improve Cancer Immunotherapy’s Effectiveness and Accessibility
A collaborative research team has synthesized a molecule that could be used as an alternative to the antibodies used in immunotherapy treatment for cancer. The study is published in the Journal for ImmunoTherapy of Cancer.
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