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Achilles’ Heel of Dangerous Hospital Pathogen Discovered content piece image
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Achilles’ Heel of Dangerous Hospital Pathogen Discovered

Researchers shed light on the structure of an enzyme important in the metabolism of the pathogenic bacterium Acinetobacter baumannii, revealing weak spots where it might be possible to attack the pathogen.
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Preclinical Data Suggests COVID-19 Vaccine Protects Against All Variants

Preclinical data for a vaccine developed to protect against SARS-CoV-2 indicates that it is effective against all variants known to date, including omicron.
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COVID-19 Vaccine Administered in Early Pregnancy Not Associated With Birth Defects

Maternal COVID-19 vaccination in early pregnancy is not associated with fetal abnormalities detectable on ultrasound, finds a study in JAMA Pediatrics.
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A Potential Therapeutic Target for Inflammatory Tissue Injury

Researchers have discovered two distinct subtypes of neutrophils and found that one of the subtypes could be exploited as a drug target for inflammatory diseases.
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Sugary Foods May Lead to Poor Oral Health

Higher intake of sugary and high glycemic load foods — like doughnuts, soft drinks, breads and non-fat yogurts — may influence poor oral microbiome health, and systemic health outcomes potentially, in postmenopausal women.
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Immune Cell Conflicts Hinder Recovery From Muscle Loss Injury

After large muscle loss injuries, like gunshots, immune cells persist at the injury site for much longer than normal, preventing muscle regrowth and repair.
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“Two-Faced” Protein Switches From Inhibitory to Activating in Genetic Disorder

Researchers have found that a key protein in B cell signaling can switch from an inhibitory role to an activating one when B cell receptor signaling is compromised in immune disorders.
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Results Are In From Trial Assessing Flu Vaccine for Heart Failure Patients

People with heart failure who received an annual flu shot had lower rates of pneumonia and hospitalization on a year-round basis and a reduction in major cardiovascular events during peak flu season.
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Method Helps To Decode the Complexities of the Human Microbiome

A new method that combines two current methods of sequencing microbial DNA has helped unlock some of the complexities of the microbiome.
CRISPR Gene-Editing Identifies Human Genes Important for HIV Infection content piece image
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CRISPR Gene-Editing Identifies Human Genes Important for HIV Infection

Scientists at Northwestern Medicine are using new advances in CRISPR gene-editing technology to uncover new biology that could lead to longer-lasting treatments and new therapeutic strategies for Human Immunodeficiency Virus (HIV).
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