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Is Genome Editing the Microbiome Just Around the Corner?
To date, CRISPR enzymes have been used to edit the genomes of one type of cell at a time. Now, the group that invented the genome editing technology has found a way to add or modify genes within a community of many different species simultaneously, opening the door to what could be called “community editing.”
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Higher Antibody Levels When COVID-19 Vaccine Administered in the Afternoon
A new study published in the Journal of Biological Rhythms demonstrates that antibody levels are higher when people receive the SARS-CoV-2 vaccine in the afternoon versus the morning.
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How Bacterial Pathogens Cope With Starvation
Researchers at Illinois provide insight into the signal transduction mechanism utilized by Staphylococcus aureus in response to host-imposed starvation.
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Four-Stranded DNA Structures Found To Play a Role in Aging Disease
Researchers have observed a protein called Cockayne Syndrome B (CSB) preferentially interacting with a special form of four-stranded DNA.
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Prokaryotic Viruses Found To Have an Important Role in Sewage Treatment
Prokaryotic viruses (phages) existing in activated sludge, a biological treatment process widely used in wastewater treatment plants, act to regulate the composition of the microbial community present.
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Nanoparticle Could Lead to More Powerful Vaccines
Researchers have designed a new nanoparticle adjuvant that may be more potent than others now in use. Studies in mice showed that it significantly improved antibody production following vaccination against HIV, diphtheria and influenza.
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Tackling Lassa Virus Infection With Structural Clues
Lassa fever is listed as a significant public health threat with high epidemic potential and no effective countermeasures. Researchers have now used structural biology to detail nine structures of the Lassa viral polymerase in different functional configurations.
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Gut Microbiota–Amyloid Relationship May Be Mediated by Immune Cells
New research from the University of Chicago points to microglia, key immune cells in the brain, as a key mediator in the relationship between the gut microbiome and b-amyloid deposits in male mice in a model of Alzheimer’s disease.
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A Chewing Gum Designed To Trap SARS-CoV-2
Researchers have created a chewing gum laced with a plant-grown protein that serves as a “trap” for SARS-CoV-2. In doing so, a new study suggests that it can help to reduce the viral load in saliva.
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Rapid Test Identifies Antibody Effectiveness Against COVID-19 Variants
Biomedical engineers at Duke University have devised a test to assess how well a person’s neutralizing antibodies fight infection from multiple variants of COVID-19 such as Delta and the newly discovered Omicron variant.
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