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Double helix structure of DNA.
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Next-Gen CRISPR Tool Produces Unprecedented Map of Human Immune Response

In a study of historic scale, scientists at Gladstone Institutes have created an intricate map of how the immune system functions, examining the molecular structures governing human T cells using the next-generation CRISPR tool known as base editing.
Drawing of human intestines on a female abdomen.
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Stomach Bacteria Infection May Increase Alzheimer's Risk

Infection with the stomach bacterium Helicobacter pylori could increase the risk of developing Alzheimer’s disease: In people over the age of 50, the risk following a symptomatic infection can be an average of 11 percent higher.
Double helix structure of DNA.
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Just a One Letter Difference in DNA Affects the Activation of the Immune System

One-letter difference in our DNA determines whether BCG vaccine provides good protection against tuberculosis or not. Researchers have elucidated how that one letter difference affects the activation and deactivation of the immune system.
Bacteria bloom on a petri dish.
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Scientists Uncover How Bacteria Generate Cellular Protein Signals During Infection

A study has identified how bacteria generate and modify ubiquitin for cell–cell communication during infection. The findings may have implications for cancer and Parkinson's research.
A smoking cigarette rests on a ledge.
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Cigarette Smoking Reduces Healthy Bacteria in the Mouth

A new study has investigated how smoking affects the oral microbiome and the effect of quitting on microbial diversity, finding that as cigarette consumption increases, the number of beneficial bacteria decreases.
A mother cutting up food for her infant.
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Eating Fish in Childhood Could Protect Against Neurodevelopment Delays

Adding fish to a toddler’s repertoire of finger foods may help protect them from neurodevelopmental delays, according to researchers at the Penn State College of Medicine.
Killer T cells surround a cancer cell.
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How Immune Cells Recognize Their Enemies

A specific subset of T cells recognize their enemies by detecting their altered cell metabolism, new research shows.
A scanning electron microscopic image of Drexel's BioFiber self-healing concrete system, showing a structural core fiber with hydrogel coating and polymer shell.
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Bacterial Veins Could Form a Self-Healing System for Concrete Infrastructure

In hopes of producing concrete structures that can repair their cracks, researchers from Drexel University’s College of Engineering are putting a new twist on an old trick for improving the durability of concrete.
A mosquito.
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How Zika Virus Does So Much With So Little

Researchers at Sanford Burnham Prebys have shown how the virus Zika does so much with so little and may have identified a therapeutic vulnerability.
Neurons shown in gold.
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Stimulating the Vagus Nerve Reduces Chronic Inflammation for Children With IBD

Non-invasive stimulation of the vagus nerve through the ear reduces inflammation for pediatric patients with inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis.
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