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Phase 3 Trial Assesses Dual-Antibody Injection's Ability To Prevent SARS-CoV-2 Infection
A Phase III, randomized, double-blinded, placebo-controlled trial will help to determine if the dual-antibody treatment, REGN-COV2, can prevent infection in individuals who share a home with someone who has been diagnosed with COVID-19.
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Why Do Some People With COVID-19 Develop Severe Disease?
New findings by scientists at the National Institutes of Health and their collaborators help explain why some people with COVID-19 develop severe disease. The findings also may provide the first molecular explanation for why more men than women die from COVID-19.
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Redesigning Existing Antibiotics To Outmanoeuver Resistant Bacteria
Researchers at UC San Francisco are tackling antibiotic resistance using a different approach: redesigning existing antibiotic molecules to evade a bacterium’s resistance mechanisms.
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A Real-Time Look at How Viruses Attack at the Single-Cell Level
A collaboration is on a mission to understand, in visual detail and with mathematical precision, all aspects of viral attack strategies, including how viruses invade host cell protein-making machinery.
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Variation in Genes Associated With Viral Entry of SARS-CoV-2 Unlikely to Influence Morbidity
To investigate clinical variability in SARS-CoV-2, a team of researchers surveyed publicly available databases of genomic variants and studied variants across multiple regional and ethnic groups in seven genes known to play roles in viral entry into host cells and recognition of viral RNA in host cells.
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Ultrapotent Compound Could Help Combat C. difficile
Scientists from Purdue University have advanced novel compounds that they have designed to help treat patients with Clostridioides difficile.
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New Brain Cell-Like Nanodevices Work together to Identify Mutations in Viruses
Researchers have built a new device that acts just like a brain cell.
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SARS-CoV-2 Interactome Reveals Likely Molecular Mechanisms of Pathogenesis
University of Alabama at Birmingham researchers, led by Shahid Mukhtar, Ph.D., associate professor of biology in the UAB College of Arts and Sciences, have now built an interactome that includes the lung-epithelial cell host interactome integrated with a SARS-CoV-2 interactome.
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182 Genes Identified That Regulate Interactions Between Cancer Cells and T Cells
Toronto scientists have mapped the genes allowing cancer cells to avoid getting killed by the immune system that paves the way for the development of immunotherapies that would be effective for larger patient populations and across different tumour types.
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$111 Million NIH Grant Awarded To Combat HIV-Associated Cancers
For 25 years, the AIDS Malignancy Consortium (AMC) has led national and international efforts to prevent and treat HIV-related cancers. Now, Montefiore Health System and Albert Einstein College of Medicine have received a five-year, $111 million grant from the National Cancer Institute (NCI) to lead this research consortium.
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