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Orange and white pills spill from a prescription bottle.
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Researchers Decode the Mechanism of Action of Hepatitis B and D Virus Inhibitor

The molecular mechanisms behind the action of the hepatitis B and D virus inhibitor bulevirtide have been revealed, potentially paving the way to more targeted treatments.
COVID-19.
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Macrophages Deep in Lungs Susceptible to SARS-CoV-2 Infection

A previously overlooked type of immune cell allows SARS-CoV-2 to proliferate, Stanford Medicine scientists have found. The discovery has important implications for preventing severe COVID-19.
Microscopic visualisation of immune cells (in green) activated by the alarmins TL1A and interleukin-33 during the onset of allergic inflammation in the lungs.
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New Study Identifies Molecule Triggering Allergic Reactions

Inflammation plays a major role in allergic diseases, affecting at least 17 million people in France, including 4 million asthmatics. One of the molecules that initiates this process in the respiratory tract has just been identified.
A bacteriophage.
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New Phage Resistance Mechanism Uncovered in the Oral Microbiome

Recently, ADA Forsyth scientists exploring the complex interactions of microbes in the oral microbiome discovered a third player influencing the phage-bacterial arms race – ultrasmall bacterial parasites, called Saccharibacteria or TM7.
Olive oil next to a plant on a table.
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Potential Therapy Identified for Gene Mutation Associated With Increased Viral Infection Susceptibility

A gene mutation associated with a rare neurological disorder and increased susceptibility to viral infections may be treatable with oleic acid.
A fractured stick of lactic acid with added ultra-high molecular weight LAHB and a stick of pure polylactic acid.
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Engineered Bacteria Produce Biodegradable Plastic

Engineered bacteria can produce a plastic modifier that makes renewably sourced plastic more processable, more fracture resistant and highly biodegradable even in sea water.
Cancer cells.
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Diversity of Bacteria in Cancer Metastases

Researchers at the Netherlands Cancer Institute have compiled a detailed catalog of bacteria living in cancer metastases. They shed light on the diversity of these co-inhabitants and how they might interact with cancer cells and their surroundings.
A gloved hand holds four test tube vials filled with blood.
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Long COVID Can Now Be Detected in the Blood

People with long COVID have distinct patterns of inflammation detectable in the blood, which could potentially be targeted with immune therapies, reveals new research.
A strand of RNA.
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Language Model Reads the Genome and Designs More Effective mRNA Vaccines

Language models can be used to home in on partial genome sequences and optimize those sequences to study biology and improve medicine, and have designed more effective mRNA vaccines.
A person wrapped in a blanket takes prescription pills.
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UTI Oral Vaccine Offers Promising Alternative to Antibiotics

An oral vaccine against recurrent UTIs could reduce the need for antibiotic treatment.
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