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Epigenetic Rearrangements Aid in Cellular Immune Memory
A team of researchers has discovered that the memory of the immune system relies on characteristic epigenetic features and a specific 3D arrangement of the DNA in the nucleus of memory cells, allowing for a fast activation of these cells.
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A New Tactic To Take on Leprosy
Researchers have begun to understand the unique role certain immune receptors play in leprosy infections in mice, which could lead to new types of treatments for this disease and others in humans.
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Mast Cells Act Like a Sensor To Help Avoid Contact With Allergens
The function of mast cells is still a mystery. Scientists have now shown in mice that mast cells function as a sensor that signals the animals to avoid antigens, including harmful allergens, and thereby protect themselves from health-threatening inflammatory reactions.
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Our Immune System Alters Our Behavior
Immune system recognition of allergens and pathogens in the environment allows the brain to take defensive measures, such as avoidance.
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Mysterious Gulf War Illness Caused by Mitochondrial Dysfunction, Not Inflammation
Scientists contest longstanding hypothesis about mysterious illness affecting Gulf War veterans, providing first direct evidence that symptoms are driven by impaired mitochondria.
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Immune Memory Is Achieved by Epigenetic and Topological Rearrangements of DNA in Immune Cells
A team of researchers has discovered that the memory of the immune system relies on characteristic epigenetic features and a specific 3D arrangement of the DNA in the nucleus of memory cells, allowing for a fast activation of these cells.
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Damage to Breast Cancer Patients' Gut Bacteria Linked to Chemo-Induced Weight Gain
Results point the way to potentially help survivors avoid obesity-related illness later in their lives.
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New Antibiotic Target Holds Promise for Treating Resistant Superbugs
A relatively new antibiotic, AMC-109, has shown promising results in the lab as well as in clinical trials against the notoriously difficult-to-treat methicillin-resistant Staphylococcus aureus (MRSA).
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Meningeal Inflammation May Damage Brain Cells in Multiple Sclerosis
A study in mice suggests that inflammation in the brain’s barrier, the meninges, may spill over into grey matter and cause changes that can contribute to progressive multiple sclerosis (MS).
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Adapting the Delivery of Cancer Immunotherapies Could Cut Costs and Waste
A new analysis suggests that up to millions of dollars could be saved annually by altering the way immune-based cancer drugs are delivered to the body. By using weight-based doses and sharing single-use vials it could also be possible to reduce waste.
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