We've updated our Privacy Policy to make it clearer how we use your personal data. We use cookies to provide you with a better experience. You can read our Cookie Policy here.


Brain Stimulation May Improve Memory Ability in Individuals With Schizophrenia

A human anatomy model with the brain showing.
Credit: David Matos / Unsplash.
Listen with
Register for free to listen to this article
Thank you. Listen to this article using the player above.

Want to listen to this article for FREE?

Complete the form below to unlock access to ALL audio articles.

Read time: 1 minute

Most people with schizophrenia have extensive impairment of memory, including prospective memory, which is the ability to remember to perform future activities. Results from a randomized clinical trial published in Neuropsychopharmacology Reports indicate that repetitive transcranial magnetic stimulation (rTMS), a non-invasive method that uses alternating magnetic fields to induce an electric current in the underlying brain tissue, may help ameliorate certain aspects of prospective memory in individuals with schizophrenia.

The trial included 50 patients with schizophrenia and 18 healthy controls. Of the 50 patients, 26 completed active rTMS and 24 completed a sham rTMS. Healthy controls received no treatment.

Want more breaking news?

Subscribe to Technology Networks’ daily newsletter, delivering breaking science news straight to your inbox every day.

Subscribe for FREE

Investigators assessed both event-based prospective memory—remembering to perform an action when an external event occurs, such as remembering to give a message to a friend the next time you see them—and time-based prospective memory—remembering to perform an action at a certain time, such as remembering to attend a meeting scheduled in the future.

Both event-based prospective memory and time-based prospective memory scores at the baseline of the trial were significantly lower in patients with schizophrenia than in controls. After rTMS treatments, the scores of event-based prospective memories in patients were significantly improved and were similar to those in controls, while patients’ scores of time-based prospective memory did not improve.

“The findings of this study may provide one therapeutic option for prospective memory in patients with schizophrenia,” said co–corresponding author Su-Xia Li, MD, PhD, of Peking University, in China.

Reference: Xue F, Wang XF, Kong FN, et al. Effects of bilateral repetitive transcranial magnetic stimulation on prospective memory in patients with schizophrenia: A double-blind randomized controlled clinical trial. Neuropsychopharmacol Rep. 2023;n/a(n/a). doi: 10.1002/npr2.12397

This article has been republished from the following materials. Note: material may have been edited for length and content. For further information, please contact the cited source.