We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience. You can read our Cookie Policy here.

Advertisement
Fighting the Fight for Healthy Teeth
News

Fighting the Fight for Healthy Teeth

Fighting the Fight for Healthy Teeth
News

Fighting the Fight for Healthy Teeth

Read time:
 

Want a FREE PDF version of This News Story?

Complete the form below and we will email you a PDF version of "Fighting the Fight for Healthy Teeth"

First Name*
Last Name*
Email Address*
Country*
Company Type*
Job Function*
Would you like to receive further email communication from Technology Networks?

Technology Networks Ltd. needs the contact information you provide to us to contact you about our products and services. You may unsubscribe from these communications at any time. For information on how to unsubscribe, as well as our privacy practices and commitment to protecting your privacy, check out our Privacy Policy

New research published in BioMed Central’s open access journal BMC Immunology shows that odontoblast cells are part of the immune system and fight to protect teeth from decay.

Inside a tooth odontoblast cells sit between the enamel and pulp and produce a layer of dentin to protect the pulp from wear and infection. This research shows that, when under attack from bacteria, the odontoblast cells also orchestrate an immune response, producing antimicrobial peptides (ß-defensins) to fight the infection directly, protein messangers (chemokines) which recruit white blood cells to the site of infection, and pro-inflammatory signalling  proteins (IL-1β, IL-1α, and TNF-α) which, in turn, initiate an inflammatory response.

Dr Orapin Horst  also found that the odontoblast layer produced proteins involved in the down-regulation of this inflammatory response, such as toll-interacting protein (TOLLIP), TGF-α, and IL-10, which help protect the underlying pulp from inflammatory damage.

Dr Horst says that “For the first time we now have targets to control  irreversible inflammatory damage to teeth”.

Advertisement