High Level of Antibodies Linked to Cognitive Decline
News Mar 28, 2013
The researchers used a test called infectious burden (IB) on blood samples from 1,625 participants in the multi-ethnic Northern Manhattan Study; the average age of participants was 69. IB measures exposure to three viruses (herpes simplex types 1 and 2 and cytomegalovirus) and two bacteria (Chlamydia pneumonia and Helicobacter pylori).
The subjects were given a cognitive assessment, the Mini-Mental State Exam (MMSE). Those who had higher IB scores had a 25 percent higher risk of scoring more poorly on the MMSE.
“The link was strongest among women, those with lower socioeconomic status, and—most notably—those who did not exercise,” said lead author Mira Katan, MD, postdoctoral fellow at the Neurological Institute at Columbia University Medical Center.
As the population ages, clinicians will have an ever greater need for ways to determine risk of cognitive loss. The link between elevated IB and cognitive loss could provide one such tool.
“Infectious burden and cognitive decline” was published in the March 26, 2013, print issue of Neurology, the medical journal of the American Academy of Neurology.
The number of young adults living in their own household has dropped dramatically in the last decades in the United States, and a growing proportion of young people will move back in with their parents at some point in time. These “boomerang” moves are associated with an increase in depressive symptoms, a recent MPIDR study suggests.
From online forums to community groups, research and experience shows people are more willing to insult and use menacing language online than in person, especially when there’s the protection of anonymity behind a computer. New research indicates that people react less strongly to malicious speech on digital platforms and see the victims as less “harmed” than if the words were said directly to a person.
International Conference on Cell and Structural biology
Jul 15 - Jul 16, 2019