We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience, read our Cookie Policy

Immune Cells Put Into Gear by Molecular "Clutch"

News   Jul 23, 2019 | Original story by the University of Warwick for the National Centre for Biological Sciences.

 
Immune Cells Put Into Gear by Molecular "Clutch"

The composition of LAT clusters changes on its travel towards the center leading to changes in their binding to the actin network: in the distal supramolecular activation cluster (D-SMAC) zone, LAT clusters contain Nck and WASP and bind strongly to actin network leading to their transport together with the actin retrograde flow; at the transition to the peripheral SMAC, characterized by concentric organized acto-myosin arcs, LAT clusters loose Nck and WASP leading to a weaker interaction with actin allowing them to be swept towards the central SMAC by the radially constricting acto-myosin arcs. Credit: Dr. Darius Köster, University of Warwick.

 
 
 

RELATED ARTICLES

Hypoxia Linked to Fish Stock Declines

News

If you want to know how climate change and hypoxia -- the related loss of oxygen in the world's oceans -- affect fish species such as the economically important Baltic cod, all you have to do is ask the fish.

READ MORE

Super-resolution Microscopy Takes a Turn of Speed With Ghost Imaging

News

A new nanoscopy approach is poised to capture biological processes occurring inside cells at submillisecond speeds.

READ MORE

Skipping the Sweet Treats Might Bust the Holiday Blues

News

Eating added sugars – common in so many holiday foods – can trigger metabolic, inflammatory and neurobiological processes tied to depressive illness.

READ MORE

 

Like what you just read? You can find similar content on the communities below.

Analysis & Separations Cell Science

To personalize the content you see on Technology Networks homepage, Log In or Subscribe for Free

LOGIN SUBSCRIBE FOR FREE