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Missing Link in Lupus Illuminated

News   Oct 11, 2018 | Original Story from Emory University.

 
Missing Link in Lupus Illuminated

Autoreactive CD27 - IgD - CXCR5 - CD11c + (DN2) B cells expand in lupus patients -- DN2 cells derive from naive cells and are poised to generate plasmablasts -- DN2 B cells are hyper-responsive to Toll-like receptor-7 signaling. Credit: From Jenks Immunity 2018.

 
 
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