Ono and Medarex Enter into Second Antibody Development Collaboration
News Mar 30, 2006
Ono Pharmaceutical Co., Ltd. and Medarex, Inc. have announced that they have entered into a collaborative agreement to research and develop a fully human anti-SDF-1 antibody for the potential treatment of multiple indications.
This is the second antibody development collaboration between Ono and Medarex. Anti-SDF-1 antibodies have been raised utilizing Medarex's UltiMAb Human Antibody Development System®.
Under this collaboration, Ono and Medarex expect to jointly work toward potential commercialization of a fully human antibody.
The two companies plan to share the costs and responsibilities of research and product development up to the completion of a Phase II clinical study.
Thereafter, each company will be fully responsible for any continued development and any commercialization in its exclusive territory; Medarex's exclusive territory is North America, and Ono's exclusive territory is all areas outside of North America.
"We are pleased to work with Ono as we continue to develop MDX-1106, our anti-PD1 antibody product candidate, and now for the development of a potential anti-SDF-1 antibody product candidate," said Dr. Donald L. Drakeman, President and CEO of Medarex.
Synthetic Material That Detects Enzymatic ActivityNews
Scientists integrate protein and polymer building blocks to create stimulus-responsive systemsREAD MORE
Regenerative Medicine Meets Clever Engineering to Accommodate Bone GraftsNews
Personalized bone grafts developed to repair bone defects from disease or injuryREAD MORE
Broadly Acting Antibodies Found in Blood of Ebola SurvivorsNews
Scientists have discovered a set of powerful, broadly neutralizing antibodies in the blood of Ebola survivors. In animal studies, two of these antibodies provided substantial protection against disease caused by the three species known to cause fatal human illness.READ MORE