Roche Files IND for Genmab Antibody
News Dec 14, 2005
Genmab A/S has announced that its partner Roche has filed an Investigational New Drug application (IND) with the US Food and Drug Administration for a Genmab antibody developed under the companies' collaboration.
This is the ninth milestone Genmab has achieved under the agreement. Genmab will receive a milestone payment from Roche which does not influence Genmab's financial guidance for 2005.
Under the agreement with Roche, Genmab utilizes its broad antibody expertise and development capabilities to create human antibodies to a broad range of disease targets identified by Roche.
Genmab receives milestone and royalty payments based on products. In certain circumstances, Genmab may obtain rights to develop products based on disease targets identified by Roche.
If all goals are reached, the value of the collaboration to Genmab could be USD 100 million, plus royalties.
Roche has selected four Genmab antibodies as clinical candidates and this is the first of the four to enter the clinic.
"This is the sixth Genmab product to enter clinical development," said Lisa N. Drakeman, Chief Executive Officer of Genmab.
"This move to clinical development is a testament to Genmab's antibody discovery skills as well as Roche's skill in identifying valid disease targets."
Schizophrenics' Blood Contains RNA From More MicrobesNews
The blood of schizophrenia patients features genetic material from more types of microorganisms than that of people without the debilitating mental illness, research at Oregon State University has found. What’s not known is whether that’s a cause or effect of the severe, chronic condition that strikes about one person in 100.READ MORE
Antitumor Immune Function in Liver Controlled by Gut MicrobiomeNews
Scientists have found a connection between bacteria in the gut and antitumor immune responses in the liver. The study showed that bacteria found in the gut of mice affect the liver’s antitumor immune function. The findings have implications for understanding the mechanisms that lead to liver cancer and for therapeutic approaches to treat them.READ MORE
You Are What Your Mother EatsNews
While many factors, such as the age of the mother, overall health and genetics ultimately play a role, the correlation between a mother’s nutrition habits and metabolism has been proved to directly impact the growth of her child. And researchers believe they may be one step closer to knowing why.READ MORE