Latest Posters
Poster
Correlations among the Toddler Gut Microbiome and Health Status Variables
Establishment and succession of the human microbiome begins at birth and microbial composition adapts alongside human development and growth. Development of a healthy signature microbial community has significant effects on health.This study followed 18 very low birth weight (VLBW) infants, measured initially in the from Neonatal Intensive Care Unit (NICU), at the age of two to three years old.
Poster
C1 Complement mediates human cord blood serum derived APP α-secretase cleavage activity in vitro
Our results indicate that CBS contains proteins that promote α-secretase like enzymatic activity. LC-MS/MS analysis in CBSF and AgBSF revealed the presence of 142 proteins of which C1 subunits and alpha-2-macroglobulin showed significantly greater levels in αCBSF compared with αAgBSF. further study showed,C1 subunits can enhance sAPPα production and Aβ reduction in cell culture condition
Poster
Bacillus cereus in the Hematologic Malignancy Patient: Case Report and Review of the Literature
This is a case report describing neutropenic colitis (typhlitis) caused by Bacillus cereus in a patient with Acute Myelogenous Leukemia (AML).
Poster
Anti-CelTOS Transmission Blocking Activity in vivo and in vitro against P. falciparum by Epitope-specific Monoclonal Antibodies
The presence of CelTOS mAb significantly inhibited oocyst development in mosquitoes in both in vivo and in vitro assays. Importantly, the experimental results with an innovative in vivo humanized mouse model confirmed that circulating anti-CelTOS antibody effectively inhibits P. falciparum ookinete development to oocyst in mosquitoes. These results support the development of CelTOS as a transmission blocking vaccine.
Poster
Alterations in Immunophenotype of Autoimmune-prone Hypomorphic RAG-deficient Patients with CID-G/AI Phenotype
Patients with partial deficiency of recombination-activating genes 1 or 2 (RAG1/2) can present with a wide spectrum of primary immunodeficiencies including combined immunodeficiency with granuloma and/or autoimmunity (CID-G/AI). Prior case reports have highlighted alterations in B and T cell compartments; however comprehensive characterization of these cell populations with focus on autoreactive-prone subsets has not been reported.
Poster
Using Remote Sensing Methodologies to Combat Schistosomiasis in Northern Senegal
Schistosomiasis is associated with poverty, a lack of clean water and sanitation and is is transmitted through snail vector. Remote sensing methodologies were used to identify types of vegetation that are significantly associated with snail presence as previous studies had shown that removal of certain aquatic vegetation decreased the prevalence of schistosomiasis in nearby villages.
Poster
Screening of ALDH2 Interactome by Combined Immunoprecipitation and Mass Spectrometry
ALDH2 may have an unidentified protein interaction network, which would help elucidate its importance in various cellular functions. The combination of immunoprecipitation and mass spectrometry will give us insights that could not be easily attained otherwise.
Poster
Nitrogen metabolism in Mycobacterium tuberculosis: a systems-based approach
Previous studies suggested that Mycobacterium tuberculosis obtains nitrogen from a diverse range of intracellular nutrients including amino acids. Here, we use a novel system’s based three-pronged approach to define pathways for uptake and assimilation of nitrogen.
Poster
Role of Elevated Airway Glucose (and Other Biochemicals) in Bacterial Infections
Bacteria that live in the airways need something to eat: they mainly use host derived biochemicals, for example glucose. When levels of airway biochemicals are dysregulated, bacterial colonisation increases, enabling infection. We investigated how changes in airway glucose effect bacterial infection.
Poster
Flesh Eating Bacteria causing Necrosis: Sources and Prevention
Necrotizing fasciitis is a serious bacterial skin infection that spreads quickly and kills the body's soft tissue. The infection is commonly called "flesh-eating infection," The bacteria include group A Streptococcus, Klebsiella, Clostridium, Escherichia coli, Staphylococcus aureus and Aeromonas hydrophila. Bacteria infect flat layers of a membrane known as the fascia, which are connective bands of tissue that surround muscles, nerves, fat, and blood vessels.
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