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AAV Purification Techniques To Advance Gene Therapy

AAV Purification Techniques to Advance Gene Therapy

Adeno-associated viruses (AAVs) are the vector of choice for the delivery of many gene therapy drugs. However, their bioprocessing can require multiple costly purification steps to remove potentially dangerous process-related impurities. 

Now, improved workflows promise to deliver high-yielding, quality AAV-based products from high-titer starting samples in single workflow step. With the latest affinity solutions, biopharmaceutical companies can accelerate drugs to clinic with greater speed and safety. 

This poster highlights several methods by which the downstream purification of viral vectors can be improved using chromatography methods to analyse and purify multiple AAV serotypes. 

Download this poster to learn more about: 
• Viral clearance potential and process yield improvement
• The industrial-scale development of AAV vectors
• Breakthrough analysis and elution recovery methods

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