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Accelerating Antibody Drug Development With Subdomain-Specific Affinity Chromatography

Accelerate Drug Discovery With Chromatography

Affinity purification platforms such as Protein A or L are well-established in the manufacturing process of therapeutic monoclonal antibodies. However, with the development of engineered modalities such as bi-specific antibodies, fragments and Fc-fusion proteins, challenges in the downstream process of these molecules arise.

Affinity chromatography resins, specifically developed to bind antibody-subdomain regions, can provide an alternative solution in the purification process of these new formats. Thereby, advancing the commercial production of new antibody therapeutics. 

Download this poster to discover a solution that can:

  • Perform high target purity in a single step 
  • Provide unique VHH screening technology to determine final resin properties
  • Be suitable for cGMP manufacturing processes
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