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New Unusual Amino Acid Catalog from AAPPTec
Product News

New Unusual Amino Acid Catalog from AAPPTec

New Unusual Amino Acid Catalog from AAPPTec
Product News

New Unusual Amino Acid Catalog from AAPPTec


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Bioactive peptides are often poor drug candidates because they may bind to multiple receptors causing undesired side effects or are rapidly hydrolyzed by protease enzymes.  Inserting unusual amino acids into bioactive peptides can improve the peptide’s in vitro and in vivo activity, giving them improved drug characteristics.  Unusual amino acids can improve receptor binding, enhance binding for selected receptors over other receptors, modify activity, enhance transport across cell membranes, improve solubility and increase in vivo half-life.

Unusual amino acids also are common building blocks in a variety of small molecule drug candidates, including antibiotic, thrombin inhibitors, anti-viral drugs for treating hepatitis C and HIV, anti-cancer drugs and drugs to treat cancer, multiple sclerosis and hypertension.  The AAPPTec Unusual Amino Acid Catalog has a large variety of Boc or Fmoc protected amino acids suitable for preparing combinatorial small molecule libraries for screening

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