High-Quality Tau Products for Neurodegenerative Disease Research
Tau protein is a microtubule-binding protein that plays a critical role in stabilizing microtubules in neurons, supporting their shape and function. However, in neurodegenerative diseases such as Alzheimer's disease (AD), abnormal phosphorylation of Tau leads to its aggregation into neurofibrillary tangles (NFTs), which are one of the hallmark pathological changes of these diseases. Thus, a deeper understanding of Tau's structure and function is crucial for unraveling the mechanisms of these diseases and developing new therapies.
Advancements in research methods, including in vitro experiments, cell models, organoids, and animal studies, enable scientists to investigate various forms of Tau and their effects on neuronal function. To meet this growing demand, we are proud to offer a series of high-quality Tau-related products to support researchers studying neurodegenerative diseases.
- Tau Protein: We offer full-length Tau, truncated Tau, mutant Tau, and phosphorylated Tau proteins, all rigorously validated by SDS-PAGE, SEC-MALS, and ELISA, suitable for structural biology research and drug screening.
- Pre-formed Fibrils (PFFs): Our PFFs are produced using high-purity monomers, verified by electron microscopy and ThT fluorescence for aggregation morphology and recruitment activity, ideal for modeling Tau aggregation in cell, organoid, and animal models.
- Tau Stable Cell Line: We provide the Tau-K18 stable cell line, which expresses Tau-K18 protein, offering a robust cell model for studying Tau function in neurodegenerative diseases.
- Phosphorylated Tau (p-tau) Antibodies: Our p-tau181 and p-tau217 antibodies have the purity of over 95%, verified for binding activity in SH-SY5Y neuroblastoma cells, making them suitable for detecting phosphorylated Tau.
As the brand of ACROBiosystems that focused on neuroscience, Aneuro also offers a variety of neuroscience-related products, including neural factors, neural antibodies, iPSC-derived neural cells, multi-channel electrodes, and more, to support a wide range of neuroscience research needs.
